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ITSAN Member Blogs / Re: Blogging - Experimental treatments
« Last post by Bobcanberra on January 22, 2018, 09:55:19 PM »
Vitamin A regulates hypothalamic-pituitary-adrenal axis status in LOU/C rats.

Vitamin A deficiency induced an increased HPA axis activity in LOU/C rats, normalized by RA administration. Compared with LOU/C control rats, vitamin A-deficient rats showed a delayed and heightened corticosterone response to restraint stress. The expression of corticosteroid receptors was strongly decreased by vitamin A deficiency in the hippocampus, which could contribute to a less efficient feedback by corticosterone on HPA axis tone. The expression of 11β-HSD1 was increased by vitamin A deficiency in the hypothalamus (+62.5%) as in the hippocampus (+104.7%), which could lead to a higher production of corticosterone locally and contribute to alteration of the hippocampus. RA supplementation treatment restored corticosterone concentrations and 11β-HSD1 expression to control levels.

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Vitamin A is especially important if youíre  Th1 dominant and have low PPARy.

Vitamin A might be one of those nutrients that you can get enough of in a vegan diet if youíve got the genetic predisposition for high conversion of beta-carotene to retinol or an anti-inflammatory/Th2 immune profile.

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ITSAN Member Blogs / Re: Blogging - Experimental treatments
« Last post by Bobcanberra on January 19, 2018, 12:45:00 AM »
retinol gut lining and high/low fibre diet.
ITSAN Member Blogs / Re: Blogging - Experimental treatments
« Last post by Bobcanberra on January 19, 2018, 12:12:43 AM »
Dr. Fukaya's
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The first and the second patients are topical steroid users. The other four patients have withdrawn from topical steroids. The atrophy of epidermis can be seen in the first and fifth cases and the hypertrophy of epidermis in the third, fourth and sixth cases. Severe insufficiency of keratinization can be seen in the third and fourth cases.


Seems similar to Hyperkeratosis and maybe Keratosis pilaris. Seems some faster recovering TSW patients use Cod liver oil in there treatment.

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Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis), often associated with the presence of an abnormal quantity of keratin,[1] and also usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed to assess minor degrees of hyperkeratosis.

It can be caused by vitamin A deficiency or chronic exposure to arsenic.



Hyperkeratosis and maybe Keratosis pilaris are linked to gluten intolerance, is this do to the affected gut mucus lining because of low Vit A levels?

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"Not often enough. I stopped eating it, but dreaded winter dryness has driven me back to beef liver for relief. 3 days after a half-pound of beef liver, itching is gone. KP is smoothing out, chapped lips are healing.
Yes! I've had KP on the backs of my arms since I could remember and once I went paleo (gluten-free) it was gone almost overnight.
Ok, after a month of nothing but chicken livers, a small amount of KP started to return. 2 weeks of beef liver and it's gone again. Yep, it's copper.
Could be better quality vitamin A... supplemental vitamin A always caused acne, the same with vitamin E. Liver (for vitamin A) and red palm oil (for vitamin E) seem to cause only good things. Ahhh, more parentheses!"

Vitamin E seems to play a large role.

Copper seems to play a large role.

Low fibre diets cause bacteria to eat gut mucus layer.

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ďThe lesson weíre learning from studying the interaction of fiber, gut microbes and the intestinal barrier system is that if you donít feed them, they can eat you,Ē says Eric Martens, Ph.D"

1. Remove all gluten in diet
2. Use Vitamin E cream (home made cream)
3. Eat two tablespoons per day pumkin seeds (Vit E)
3. Eat Beef liver 3 times per week (high levels of retinol and Copper)
4. High fibre diet using veggies as fibre source.

Note: synthetic supplements will not work, need to be real source.
ITSAN Member Blogs / Blogging - Experimental treatments
« Last post by Bobcanberra on January 19, 2018, 12:09:13 AM »
Blogging information about my experimental treatments for TSW.

Canada / Re: Toronto Meet up!!
« Last post by Andrew B. on November 28, 2017, 05:07:10 PM »
Can you guys cross post to the Canada group on Facebook?

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Canada / Re: Toronto Meet up!!
« Last post by Jamnat on November 27, 2017, 11:23:37 PM »
Hi All,

I won't be able to make it anymore on Thursday evening since I've been asked to visit a mid showcase for clients at work and it's conflicting with this time (to be fair Gwen asked which days would work best it's something that came up after).

As for a quick update, I've been TS free since January 2013 and had it the worst until August 2014 where I finally was able to have periodic remissions before another flare would kick in. I was able to re-build my life after being bed ridden for a year and half and have recently in the past 4 months been grateful for a chance to prove myself in a relevant field of work that I have been working towards since my TSW.

It's been a hard few years. Anyone who is currently going through the worst of it and is committed in wanting to see the light at the end of the tunnel; do your best to find support from whom you can turn to, whether its your family, friends and any helpful physician who will listen and monitor you to prevent any serious infections while your skin, organs and body is having to go through this very demanding and painful time.

I also took my healing and bed ridden time as a way to work on my spiritual and emotional self. Meditating when you can, and learning about health in general and educating ourself is what gave me hope to keep going. I found I was able to build my intuition and internal confidence through this turmoil. I also feel everyone heals differently. My usage was never more than 1% hydrocortisone and protopic on my face and Betamethasone dipropionate on areas on my body. I still looked like a 2nd degree burnt victim for years going through withdrawal.

At the moment, near the end of 2017, I feel like I can build my life again and that's where most of my energy is now being focused on. I am totally down to meet up for coffee with anyone who needs support one-on-one, unfortunately I won't be able to make it this Thursday.

My love and well wishes are with anyone still going through this. Wishing you all the best with healing and with feeling healed too!

Canada / Toronto Meet Up! Nov. 30th!!
« Last post by Gwen on November 27, 2017, 11:53:00 AM »

Hi All!

It's been a very long time since we all got together. I'm sure at this point we're all at very different stages...hopefully healed or getting close. There's been much interest in getting together again to share our stories and struggles.

Looks like it's finally happening on Thursday November 30th at our usual place...Baka Cafe, 2256 Bloor St. W, Toronto @ 6:30 till closing (9pm). We won't be upstairs this time, but a space will be reserved for us in their new section facing Bloor St, ground floor. Lots of street parking or take subway to Runnymede Station and walk one block west.

I won't be sending out anymore private messages, so please check the ITSAN site for any last minute changes or cancellations before you head out.

Please RSVP so we know how many seats to save!!

Looking forward to seeing you all!

Canada / Re: Anyone from vancouver bc?
« Last post by CleanQueen on November 23, 2017, 12:12:54 AM »
Hi, Iím Carol from Surrey BC. Have u done tyenol. Two naturopath s told me itís a tyenol reaction but doctors wonít admit it. I too had those burn like marks on my face and thatís what it felt like. My daughter had it on her neck had had not used any steroid creams. Very puzzling. I have used steroid creams for eczema but from time to time also. Have stopped all now and wonít take tyenol again just in case.  I was taking it for severe broken wrist and thatís when my face broke out in those burn like marks .
Asia / Re: Anyone from Hong Kong here?
« Last post by Bkchu on July 18, 2017, 11:25:25 PM »
I am also 4+ years in TSW and have seen over 10+ TCM doctors, but so far none can completely cure my symptoms. I still flare on my face, neck and arms. What's your experience with those TCM doctors?
ITSAN Member Blogs / 5 years & 3months in
« Last post by Y-Sho (UK) on July 15, 2017, 08:01:00 AM »
Hello Everyone!

I want to share my on going journey with everyone here.  Its been 5 years 3 months; but am nearly there!!

I saw big improvement on my face a little over a month ago, so I decided it was time to go & preach  :say_lol: to the world as it were and create more awareness.

Please subscribe, comment and like the vlogs [/u]so that the vlogs get more visibility; thus getting to those who need to hear and see the repercussions of topical steroids.

Thanking you in advance.

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